Infection Of Bladder And Kidneys
Yeast infection of the urinary tract is
mainly affecting the bladder or the kidneys.
Patients who are diabetic, cancer patients or patients
who are immunocompromised (AIDS, chemotherapy for leukemia, immunosuppressive
drugs for transplanted organs) are more susceptible for yeast infections of the
Yeast infection of the bladder
the bladder Candida infections are usually due to manipulation with Foley catheters
that are given in hospitals for procedures, during periods of unconsciousness
in the Emergency Department or during labor and delivery. Also antibiotic therapy
to treat bacterial infection of the bladder will often be followed by yeast infections.
The patient usually experiences frequent
and painful urination with small amounts of urine each time, urgency and possibly
pain in the center of the lower abdomen. A urinary culture will often lead to
Fluconazole at a dosage
of 150 mg to 200 mg daily is given for a period of time(1 to 4 weeks). However,
there can be liver toxicity and other toxic side-effects and the physician has
to balance this in relation to the benefit of the treatment.
Yeast infection of the kidneys
infections of the kidneys originate usually from spread by the blood stream. Any
yeast bugs that would have originated from the gut will be transported by the
blood into the kidneys and as the kidneys filter the blood, will infect the kidney
tissue. Again, patients with immune deficiencies as mentioned above are affected
more seriously and more commonly. Also, patients who have indwelling catheters
in their veins or arteries are particularly at risk for yeast infections of the
kidneys as a yeast infection from the tips of such devices can spread via the
blood stream to both kidneys.
It can be
very difficult for the physician to diagnose blood born yeast infection of the
kidneys as the only symptom might be a fever resistant to antibiotic therapy.
Blood tests would show a deteriorating renal function and a midstream urine culture
would grow Candida albicans. Sometimes fungus balls develop in the origin of the
ureter and as they migrate further down this may lead to an obstruction with renal
colic like pains. Associated with this would be blood in the urine. If treatment
is not given swiftly or the diagnosis not recognized, the yeast infection will
spread through the blood stream into other organs such as the liver, the spleen,
the brain, the eyes and the skin. It can also lead to septicemia and shock.
Yeast in urine (candiduria) is best treated with fluconazole (brand name: Diflucan)
for 1 to 2 weeks. However, if the specialist( usually the urologist or nephrologist)
has determined that the yeast infection is established in the kidney tissue, then
a higher dose and longer treatment schedule is needed to eradicate the yeast infection
from the kidneys. In the first few days a course of intravenous amphotericin B
might have to be given. Subsequently the patient can then be switched to oral
fluconazole of 400 mg or higher per day until the infection has cleared. In these
life threatening situations higher than usual doses of the antifungal have to