Vitamins, Minerals and Supplements

Vitamins have long been recognized as an essential part in the nutrition team . From the tentative gropings, where sailors recognized that limes prevented scurvy, to the solid research data surrounding vitamin C by Linus Pauling, we have come a long way.

There is a catalogue of vitamin preparations, minerals and supplements available to us, and vitamin sales are no longer the domain of health food stores: supermarkets have a section of vitamins and nutritional supplements, and the variety can be confusing to the consumer. Yet it is a fallacy to believe, that we must acquire all the varieties in capsule or tablet form. With proper food intake we get the essential vitamins and minerals, and we are going back to Hippocrates again, who suggested that food be our medicine. With today's knowledge base we have a fairly clear understanding how vitamin supplementation prolongs life. Life expectancy seems to be determined genetically and depends on the telomere length. This is a small appendix to the chromosomes in each cell, which assists in cell division and stability. At birth our telomeres are the longest, but with each cell division the telomeres shorten a tiny little bit. Ref. 8 has provided the first evidence on a large population that daily vitamin supplements led to a 5.1% longer telomere when compared to people who did not take supplements. This translated to 9.8 years less aging when compared to the population with no supplement use. The same study also found that micronutrients from food were not related to telomere length with the exception of vitamin C and E. The authors (Xu et al.) concluded that multivitamin use is associated with slower biological aging due to longer telomeres. It was known before that in our lifetime each cell can only perform so many cell divisions (the "Hayflick limit").
This is the reason why under the best circumstances (good genetics, healthy life-style, good nutrition, regular moderate exercise, natural hormone supplementation to prevent premature aging) we are still limited to a life expectancy of not more than 120 years. If you incorporate the supplements listed below your chances are much better to reach this goal due to the positive effect on your telomeres.

Detoxification:

Before you think of supplementing, the body needs to be detoxified so that the nutrients and supplements can access the cells and do their supportive work. Books like "Breakthrough" (Ref.8) by Suzanne Somers have reviewed newer insights of antiaging medicine. This points out the importance of detoxifying the body from heavy metals like mercury, lead and cadmium. Chelation therapy with vitamin C and Glutathione, or with EDTA can be used to remove some of these heavy toxic metals.

Undeniably there are times where vitamins should be supplemented: patients with pernicious anemia benefit from vitamin B 12 injections. Pregnant mothers are encouraged to take prenatal vitamin supplements. A crucial supplement in pregnancy is folic acid, which reduces the likelihood of spina bifida in the baby. It is further known that in infancy the baby will not get enough vitamin D in milk, and accordingly the vitamin is administered as drops in a bit of formula or baby food. Vitamin C has also been associated with benefits in the cold and flu season.

Multivitamin preparations are of importance, where our food intake is just not quite enough to meet the demands: pregnancy, as discussed before, is such a situation, but breastfeeding a baby puts high demands on the nursing mother.

Anybody recovering from an illness will benefit likewise from a multivitamin supplement, and whoever is not eating properly, which can be the case during stress or travel, will do well using a well balanced vitamin supplement. Vitamins are not miracle drugs. They can boost our resistance to illness and contribute to our well being. Consider them like insurance. They can be your ally, but you are still having to do your part with good nutrition and a healthy lifestyle. Do not fall into the trap of starting your day with a big array of supplements. More is usually not better, and exaggerated doses of vitamins can be harmful: for instance, huge doses of vitamin A will have toxic effects on your liver, which is not exactly a prescription for health and energy. Too much calcium can significantly raise your risk for developing kidney stones. It does not mean that you now turn around and avoid any vitamin supplement. What you need is balance and moderation, whether it comes to food intake or to supplements. This has been only a short overview regarding vitamins and supplements and this is summarized in the table below as well. However, there are very good other websites that discuss this topic in much more detail. Here is one gives an overview regarding vitamins.

One of the more interesting new developments is the supplementation with amino acids that help the body to build up the human growth hormone (HGH), which may postpone aging.

As stated before, most of your vitamins will come from your food. There are some vitamins, which are like a form of insurance contributing to your health (Ref. 1, p. 276):


Vitamins and supplements, your basic "life insurance"

Fish Oil

important for omega-3 fatty acids, can be taken in capsule form or as oil; 400 mg of EPA (Eicosapentanoic Acid) and ca. 200 mg of DHA (Docosahexaenoic Acid) per capsule, take two per day. Read labels,often omega-6 mixed in; omega-3 must be major part of it and should be molecularly distilled to remove cancer producing herbicides and pesticides
Vitamin Emost studies show that it is not what it used to promise: support for a healthy heart . It used to be recommened to take 400 IU per day. Unless you had a heart attack or have a cardiac risk, you likely do not need it; ask your doctor. Newer studies say that 400 IU per day is still useful when taken together with other antioxidant vitamins (synergistic action).
Vitamin Cthe "anti-oxidant"vitamin; associated with protection against colds and flus in winter, promotes wound healing. Get some Ester-C (it is better absorbed), or get some vitamin C tablets. Take 1000 mg per day.
Calcium and Magnesiumimportant for bone health in post-menopausal females. Your most inexpensive source are calcium carbonate chew-tablets like Rolaids. Four tablets per day will be enough. There were some reports in 2008 where concerns of hardening of coronary arteries were voiced, which questions the usefulness of this. Bioidentical hormone replacement is an alternative.
Vitamin B complexknown to be the "stress" vitamin; amply found in vegetables; stress is better managed by relaxation exercises and regular physical exercises. When your diet does not contain enough greens and vegetables, take it once per day.

Multivitamin supplements

Often recommended when nutrition is not adequate (or with pregnancy, breast feeding or recovering from illness). Vitamin A (about 3,500 IU), Vitamin B1, B2, B3, B5, B6 and B12 as well as folic acid and Biotin would be useful to take as a multivitamin supplement as tablets or in liquid form (made from powder) for anybody on a daily basis

Resveratrol

Antioxidants which occur in the skins of grapes, often combined with Ellagic Acid (e.g. in trophic); a powerful anti-oxidant, prevents heart disease and cancers. 200 mg per day
Coenzyme Q10 200 mg once per day; supports heart health and is vital for cellular energy production
Vitamin D3This has been recently found to be very powerful in preventing a multitude of cancers; take 2000 IU or more (best 5000 IU) once per day
D-Ribosethis is a special sugar; a flat teaspoon once per day increases energy and endurance. In fibromyalgia it may give some relief for pain in higher doses (a flat teaspoon two to three times per day)
Melatonine important for the body to recuperate, very valuable to enhance restful sleep and a powerful anti-oxidant . It actually is a hormone from the pineal gland and it makes other hormones work better (thyroid and steroid hormones, important in anti-aging medicine). 1 to 3 mg at bedtime.
L- Carnosinegood support to cell function and assisting neurological function. 100 mg per day can be recommended. Often sold as 500 mg capsules; in this case the content of the capsules has to be divided
L-CarnitineL-Carnitine: This is not an antioxidant, but a good support for muscles, including the heart. Two 500 mg capsules per day are used for anti-aging
Alpha Lipoic Acid100 mg per day are a desirable addition to the regimen you are already taking
Phosphatidyl SerineProbably one of the best weapons against cognitive decline. For prevention purposes in persons without cognitive decline 100 mg per day. 200 to 300 mg for early Alzheimer patients. With the higher doses a bitter taste sensation can occur (harmless), simply reduce the dose.
With this approach you will not empty out your wallet or overfill your medicine shelf. And as I mention the medicine shelf, it is important to note, that vitamins and supplements should be stored away from children. The interesting colorful capsules that are beneficial in small amounts can pose a hazard in an overdose for children!

The list of vitamins and supplements may look slightly intimidating at first glance. It may be easiest to gradually build up the supplementation program. If a lineup of capsules is simply too much to stomach in one setting, it is best to distribute the supplementation over the day: one helping with breakfast and one with dinner. It is important to stay compliant. Haphazardly taking or forgetting the supplements will not do much for you. Remember that taking these high potency supplements along with nutritious food will defend your body from the aging effect of free radicals. Discuss supplementation and any questions surrounding the use of supplements with your health care provider before you embark on a program. Once you have decided to purchase supplements, read labels carefully. Staff at health food stores can also be a helpful source of information.

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Disclaimer:

This outline is only a teaching aid to patients and should stimulate you to ask the right questions when seeing your doctor. However, the responsibility of treatment stays in the hands of your doctor and you.

References:

1. B. Sears: "The age-free zone".Regan Books, Harper Collins, 2000. Also see Dr. Sears' site.

2. B. Sears: "Zone perfect meals in minutes". Regan Books, Harper Also see Dr. Sears' site.

3. B.J. Wilcox, D.C. Willcox and M. Suzuki: "The Okinawa Program."    Clarkson Potter,2001, N.Y., U.S.A.

4. E.L. Rossi: The psychobiology of mind-body healing. Norton &Co.,   1986, N.Y., U.S.A.

5. Vitamins and Foods. Audio-Digest Family Practice Vol 49, Issue 29,    Aug.7, 2001.

6. P.C. McGraw: Life strategies. 1999, Simon&Schuster Source, N.Y.,    U.S.A.

7. B. Sears: "The top 100 zone foods". Regan Books, Harper Collins,   2001. Also see Dr. Sears' site.

8. Suzanne Somers: "Breakthrough" Eight Steps to Wellness-- Life-altering Secrets from Today's Cutting-edge Doctors", Crown Publishers, 2008

9. Q. Xu et al. Am. J. Clin. Nutr. 2009; 89: 1857-1863.

Last Modified: July 24, 2010